The research program is very broad and ranges from basic molecular biology of the (tumor) cell to clinical bed-side research. Groundbreaking discoveries in the laboratory can directly be explored for their ability to improve cancer treatment by (pre)clinical studies. This interaction between the scientific disciplines creates a stimulating atmosphere.
Researchers at Amsterdam UMC
Researchers at NKI-AVL
Studying the genes and proteins involved in pathways governing the proliferation and behaviour of cells results in better understanding of tumor development, progression and therapy resistance. It may also yield markers that can be used to detect cancer at an early stage and to predict its course and response to therapeutic interventions.
Improvements of clinical care are based on improved detection and development of innovative therapies and personalized treatment strategies. The emerging and rapidly growing fields of (molecular) imaging and genomics are providing new opportunities for the development of highly valuable indicators for diagnosis and prediction of disease. Another important research focus is quality of life of cancer patients and survivors.
Research carried out within the OOA participating institutes has an excellent (inter)national status, as demonstrated by the large number of research projects granted in open national and international calls, and the large scientific output of more than 2000 publications each year.
